Human intestinal epithelium under drug stress illustrating preclinical GI toxicity screening

Why GI Toxicity Slips Through Preclinical Screening

Ask a program lead which toxicity they are most afraid of finding late, and the gut is rarely the first answer. It should be closer to the top. Gastrointestinal toxicities are the most frequently encountered clinical adverse events across drugs in development, and when they show up they do not just bother patients, they cap […]

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