RepliGut® Systems are a series of human primary cell model systems that recreate the human gastrointestinal epithelial cell barrier, representing multiple regions of the gut. Models deliver results that mimic in vivo response across a range of pharmacological applications including inflammation, toxicity, bioavailability, barrier function, and more.
The RepliGut® Difference
RepliGut® Models are available through services or kits
Human intestinal cell barrier model is organized as a single polarized layer of differentiated epithelial cells with tight junctions
RepliGut® Planar models are polarized monolayers that express tight junction proteins. All major cell lineages in physiologic ratios can be achieved.
Ethically sourced biobank consisting of multiple intestinal regions from multiple donors enabling both cross-region and cross-donor studies
Different demographic backgrounds to further enhance study data
Work with the same donor for multiple projects
Multiple regions available from small intestine and colon
Ethics Committee approved organ procurement
Whether you know exactly what you need, or want our project leads to consult, we are prepared to deliver superior results using RepliGut® Systems. Our supportive and consultative approach to project management leaves you in good hands.
Efficient and effective project design guided by project leads with hands-on experience
High success rates with reliable timelines and consultation throughout.
Full visibility to ongoing work with frequent communication.
Supportive environment of collaboration, a key ingredient to driving valuable, actionable insight.
RepliGut® kits are available in both 12-well and 96-well plate formats with semi-permeable membrane inserts to accommodate experimental need. Each membrane insert is pre-coated with a biomimetic scaffold that optimally supports culturing these specialized intestinal epithelial cells.
RepliGut® kits are sold complete with the cells, plates, and media needed to culture this unique human intestinal epithelial model in your own facility.