Poster: GB004 Exhibits Protective Effects Directly on Epithelial Cells Using Ex Vivo Organoid and Monolayer Cultures

Client Kristin Taylor Meadows and colleagues from Gossamer Bio used RepliGut^® Planar to established conditions for inducing inflammation response using TNFα.  Using this model, they show how GB-004, a novel compound in development for treating ulcerative colitis reduced the destructive effects of TNFα on epithelial barrier integrity