November 30, 2020
Enhancing Human Gut Tissue Models through Gene Editing
Enhancing Human Gut Tissue Models through Gene Editing
November 10, 2020
Increasing the Efficiency of Drug Development With Preclinical Testing Using Human Intestinal Stem Cells
Increasing the Efficiency of Drug Development with Preclinical Testing Using Human Intestinal Stem Cells
October 23, 2020
Characterization of a Novel Human Primary Intestinal Epithelial Monolayer Platform in Response to Cytokine Challenge (Poster)
The ability to grow and expend primary human epithelial cells in vitro has been a significant advancement in the field of gastrointestinal biology. The ALTIS RepliGut® Planar system uses a proprietary biomimetic scaffold on a porous membrane to form a human intestinal epithelial monolayer...
October 22, 2020
Evaluating Microbiome Therapies with Intestinal Cell Models
Evaluating Microbiome Therapies with Intestinal Cell Models
September 29, 2020
Accelerating Drug Development with Microphysiological Systems (MPS)
Current preclinical testing using assays based on cancer cells and animal models often results in high failure rates for drug candidates in the clinic. Microphysiological systems like Altis’s RepliGut® human intestinal tissue model more accurately reflect human physiological environments, enabling more efficient and cost-effective drug discovery and development.