INCREASING THE EFFICIENCY OF DRUG DEVELOPMENT WITH PRECLINICAL TESTING USING HUMAN INTESTINAL STEM CELLS

Due to a lack of robust in vivo gut models, animal studies are generally required to evaluate gut toxicity. However,these studies can be lengthy and expensive and may not accurately recapitulate the behavior of the human gastrointestinal tract. Drugs are thus often developed with undesired gut side effects that are not apparent until clinical trials...

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